Genomics, Bioinformatics & Medicine
Stem Cell Slides
Stem Cell Lecture Video
Reprogramming of human somatic cells to pluripotency with defined factors Park et al, (2008) Nature 451, January 10, pp 141- 147.
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors Takahashi et al. (2007) Cell 131, 861-872.
Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells Yu et al, (2007) Science 318, 1917.
Strategies and New Developments in the Generation of Patient-Specific Pluripotent Stem Cells Yamanaka, REVIEW (2007) Cell Stem Cell 1. July 2007 pp 39- 49.
Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells Lujan et al. Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2527-32.
Stem Cell Niche: Structure and Function. Li and Xie (2005) Annual Review of Developmental Biologyh 21, p 606-663.
Stem Cell Therapeutics. Singrec et al. 2008 Stem Cells Vol 1 pp. 313-328.
Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells. Sun N, et al. (2009) Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15720-5.
Noninvasive diagnosis of fetal aneuploidy by shotgun sequencing DNA from maternal blood. Fan et al. (2008) PNAS 105, 16266-16271
Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors. Soldner et al. (2009). Cell. 2009 Mar 6;136(5):964-77.
Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Kim et al. (2009) Cell Stem Cell. 2009 Jun 5;4(6):472-6.
The immortal strand hypothesis: segregation and reconstruction. Rando, TA (2007) Cell. 2007 Jun 29;129(7):1239-43
High incidence of non-random template strand segregation and asymmetric fate determination in dividing stem cells and their progeny. Conboy, MJ, Karasov, AO, Rando, TA. (2007) PLoS Biol. 2007 May;5(5):e102.
Mutation selection and the natural history of cancer. Cairns, J. (1975) Nature. 1975 May 15;255(5505):197-200.
Intraflagellar Transport Rosenbaum, J. L. and Wittman G. B. (2002) Nat Rev Mol Cell Biol. 2002 Nov;3(11):813-25.
Henry Stewart Talks
Stem cells from the early embryo (39 mins) Prof. Janet Rossant – Hospital for Sick Children, University of Toronto, Ontario, Canada
Gene expression analysis of pluripotent stem cells (25 mins) Dr. Uma Lakshmipathy – Life Technologies, USA
Stem cells derived from amniotic fluid and placenta (30 mins) Prof. Anthony Atala – Wake Forest Institute for Regenerative Medicine, USA
Hematopoietic stem cells and progenitor cells: their role in normal blood formation Prof. Malcolm Moore – Memorial Sloan Kettering Cancer Center, USA
Stem and progenitor cells from peripheral blood (45 mins) Prof. Shay Soker – Wake Forest Institute for Regenerative Medicine, USA
Stem cells from adipose tissue (40 mins) Dr. Adam J. Katz – University of Florida, USA